The story of one girl's mission to bring people together everywhere by eliminating small talk forever. This American Life producer Starlee Kine has been going around lecturing audiences on the subject. She encourages them to switch to a new system she's invented, called The Rundown.

Ira travels to Las Vegas for the World Series of Poker, gets hooked, and tries to figure out what it would mean if he'd ditch his job in radio to become a professional card player. What he learns: A professional gambler can suffer two heartbreaking losses back-to-back, costing him over $100,000, and moments later, at the casino bar, calculate the million-to-one odds of his unlikely losses...in his head.