Sometimes the inner voice telling us to do the wrong thing actually sounds like a voice. TAL producer Nancy Updike talks to people about the voices in their heads that persuade them to go astray.

In this act, writer Michael Kinsley describes harnessing the power of his own mind to deal with his Parkinson's diagnosis. Michael Kinsley is a contributing columnist for Vanity Fair and the Washington Post.

We searched for a parent who had a question for their kid...that they could only ask them after their kid was an adult. Then we found Ken Gethard, comedian Chris Gethard's dad, who had some really meaningful questions he wanted to ask his son.

Back in 2004, a reporter named David Holthouse published a remarkable story in the weekly paper he worked for, Westword. It's about something he waited his entire life to do...since childhood.

On October 13, 2002, David MacLean woke up in India with no memory of who he was or how he got there. He had no choice but to let the people who recognized him—and even strangers—fill in his identity.

Nubar Alexanian was forced to give up one thing—and then gave up another thing by choice. This story was put together by Nubar and his daughter Abby, with help from Jay Allison, for Transom.org, with funding from the Corporation for Public Broadcasting.

In 2008, reporter Chris Neary told the story of John, a soldier who returned from tours of Iraq and Afghanistan with severe PTSD, and ended up attacking his fiancee and her mother. Chris finds out how John is coping today.

Myron Jones and his sister Carol Bove explain what happened when they were teenagers, and they ended up babysitting children who didn't exist.

Host Ira Glass plays tape of two women who ended up as frenemies.They kept trying to be friends, but couldn't help themselves from fighting. Ira then speaks with psychologist Julianne Holt-Lunstad who has run scientific studies to answer the question: Why don't we simply end these troubling kinds of friendships? Holt-Lunstad's research also shows that these relationships are much more common than you might think.

Writer Rosie Schaap tells the story of how she ingratiated herself into the adult society of the Metroliner commuter train bar car as a teenager. She would cast Tarot card prophesies for riders, in exchange for beer.

Therapist Scott Miller tells the story of a patient who thought he was Arnold Schwarzenegger. Solving the problem required unusual treatment.

Jonathan Goldstein, for once in his life, gets to suspend time itself. He gets to freeze the hands of time, and finally come up with the right thing to say in all sorts of situations.

When Amy Silverman's daughter was born with Down syndrome, she followed the advice of all the parents she met: She signed her daughter up for "early intervention" therapy. But her daughter's progress had unexpected consequences, forcing Amy to make a choice she'd never predicted.

We tell the story of that patient, Alan Pean, and how his delusions lead him to a situation that's just as strange as the worst thoughts his mind is cooking up. This story is a collaboration with the New York Times.

The story of a woman whose husband lies to her compulsively. At some point, she starts to ask him questions that'll make him lie to her, just to amuse herself.

Brady Udall tells the story of the time he helped a stranger get his car out of a ditch. In exchange, the man promises to help him any time, for any reason—legal or not.

Ira explains that when the radio staff decided to take a test that reveals who is a psychopath, very quickly everyone came to believe that the highest score would go to either Robyn, Jane, or him.

People don't want to stop driving, no matter how old they get. This American Life producer Lisa Pollak talked with Rosyna Salerno, a 91-year-old widow, who recently gave up her license after she had a stroke. And Dan Neil, automotive critic for the Los Angeles Times, tells the story of Stirling Moss, the race car driver who, at 75, still holds the world record for completing a 1,000-mile race called the Mille Miglia.

Karen Sosnoski's one-year-old son, Anton, was born with what's known as Mosaic Down Syndrome, a rare condition where some of his cells have the extra chromosome that causes Down syndrome and other cells don't. So as he grows, he could end up having all the health risks and challenges of Down syndrome...or just a few of them.

Ira and the radio show staff get their results on the psychopath test from Dr. David Bernstein, of Forensic Consultants, LLC., who administered the test to them.

A contest held every year by a Nissan dealership in Longview, Texas in which twenty-four people stand around a $15,000 hard body pickup truck. When the starting whistle blows, each person puts one hand on the truck.

Huntington's Disease is a progressive brain disorder. There's a wide range of symptoms, but in the worst cases, people who have it can end up losing physical control of their bodies, sort of like Parkinson's Disease, and can also have mental symptoms that are like Alzheimer's or schizophrenia.

What happens when a dealer of delight gets depressed? Podcast host Tracy Clayton talks to Bim Adewunmi about the road back. (17 minutes)

Jo Giese's husband, a doctor named Douglas Forde, had spent his life caring for other people. But then he had some strokes and developed a kind of dementia.