A woman’s dog has an unexpected reaction to the pandemic, and a mother has to re-think how to teach her son to drive.

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For years one group of people has been trying to push a giant boulder to the top of a hill, like Sisyphus. But in this case, it looks like they’ve actually succeeded! David Kestenbaum spoke with four scientists who have been working on a coronavirus vaccine, one that was just shown to work.

Host Ira Glass talks to Jay Van Bavel, who recently found himself trapped in an elevator (in a very 2020 predicament).

To cope with this pandemic, producer Sean Cole finds himself turning to a movie about a pandemic, What's So Bad About Feeling Good? But the virus in this movie isn’t like any you’ve ever heard of. (20 minutes)

Two teachers find themselves thrown into a heated and ugly fight with parents right before school opens back up. Producer Miki Meek has this story from Utah.

Guest host Bim Adewunmi sits in for Ira Glass and talks to retired NASA astronaut Leroy Chiao about how a space mission compares with living alone in a one-bed apartment on earth.

We meet the doctors. Rana Awdish spends hours of each day walking the floors of the ICU checking in on her co-workers, which means that maybe more than any single person in the hospital she knows best what the staff has been going through at each stage of this pandemic. One doctor that has deep ties to Detroit is Geneva Tatem.

Nadia’s family has been isolating and disinfecting everything for weeks, and yet a cold still managed to creep in. How?

Host Ira Glass talks to a New York City ICU doctor about the little observations nurses are recording about their COVID patients to save for their families.

Couples therapist Esther Perel talks to Ira about the very particular ways she’s seeing lockdown impact couples around the world.  Listen to season three of her podcast, “Where Should We Begin: Couples Under Lockdown.” (13 minutes)