Ira interviews Ryan Knighton, a blind guy who had a very peculiar experience with a hotel room telephone. Then Ira introduces the rest of the show, which was recorded live on stage in New York City and beamed to movie theaters in the US, Canada and Australia.
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Ryan Knighton, who was interviewed in the prologue, tells this story about trying to get his daughter to understand his blindness. Ryan is the author of the memoir Cockeyed.
David Rakoff tells this story, about the invisible processes that can happen inside our bodies...and the visible effects they eventually have. David died three months after this performance, in August 2012.
Ira Glass's sister once met David Sedaris, and commented that he was much nicer than she thought he would be, given his writing. David replied, "I'm not nice, just two-faced." In this story, David shares the thoughts running through his head as he attempts to buy a cup of coffee.
Famous people are supposed to be somewhere else, invisible to us. Comedian Tig Notaro tells this story about repeatedly running into Taylor Dayne, who was a pop star in the late 80s and early 90s.