Ira tells the story of Dave, a former heroin addict who, with his friend Chris, launches a podcast inspired by the Howard Stern Show. Except it’s all about heavy drug use.

We begin with a woman whose sister has died. She has questions.

Writer Domingo Martinez tells a story from his memoir The Boy Kings of Texas, about when he was forced to face how he might look in 20 years, if he kept doing what he was doing.

Producer Sean Cole heads to Toronto to see if it was true what he heard: that lots and lots of the bartenders who used to serve him drinks there were on coke at the time. Then Sean takes Ira through a catalogue of the various professions in which people tend to get high.

Under California law, it's legal to grow marijuana for medicinal purposes if you have a doctor's recommendation. A few years ago, Mendocino County Sheriff Tom Allman was trying to find a way to deal with the proliferation of marijuana in his county.

MaryEllen Bowman tells Ira about celebrating her 22-year-old daughter Rachel Hala’s baby shower this week. A year ago, she says, she was planning her daughter’s funeral instead.

At three high schools in Palm Beach County, Florida, several young police officers were sent undercover to pose as students, tasked with making drug arrests. And this, this is the setting for a love story, reported by Robbie Brown.

For decades, the writer Alex Kotlowitz has been writing about the inner cities and the toll of violence on young people. So when he heard about a program at Drexel University where guys from the inner city get counseling for PTSD, he wondered if the effect of urban violence was comparable to the trauma that a person experiences from war.

For years, Jorge Salcedo was chief of security for the Cali drug cartel in Colombia. He was in charge of protecting some of the most powerful criminals in the world...until he decided to take them down.

At three high schools in Palm Beach County, Florida, several young police officers were sent undercover to pose as students, tasked with making drug arrests. And this, this is the setting for a love story, reported by Robbie Brown.

Joshuah Bearman tells the story of Pete's ridealong with the PI Moms, and how strange things started to happen. As he dug deeper into their operations, he learned about cases like the Candyman, where everything gets oddly and unnecessarily complicated.

Host Ira Glass tells the story of Florencia de Benito Juarez, a small town in Mexico where a new drug gang recently took over. They promised peace and tranquility, and for the most part, they're making good on those promises.

Ira reports from Glynn County Georgia on Superior Court Judge AmandaWilliams and how she runs the drug courts in Glynn, Camden and Waynecounties. We hear the story of Lindsey Dills, who forges two checks on herparents' checking account when she's 17, one for $40 and one for $60, andends up in drug court for five and a half years, including 14 months behindbars, and then she serves another five years after that—six months of itin Arrendale State Prison, the other four and a half on probation.

Nancy Updike follows up on a Haaretz newspaper story about a sting operation against a medical marijuana supplier in Israel—a case where being giving was not the best idea.

Comedian Kumail Nanjiani makes his pitch for a product you may have heard of. His story was recorded at Comix in New York.