Sarah Thyre reads author David Sedaris' "The Last Time You'll Ever Hear from Me," a story of the ultimate Machiavellian scheming.

David Sedaris has this instructive tale of how, as a boy, with the help of his dad, he tried to bridge the chasm that divides the popular kid from the unpopular...with the sorts of results that perhaps you might anticipate.

David Sedaris reads one of his funniest and most affecting stories from his book Naked before a live audience. As an adolescent boy, David feared he might be a homosexual.

David Himmel is a college sophomore and a former camper who became a counselor. He says all the best experiences of his life have been at camp or with camp people.

Bob and Dave were close childhood friends — until their relationship began to lead their peers to believe that it might be more than a friendship. The accusations led to Dave turning on Bob.

Alix Spiegel tells the story of her friend Jayna, who made a Faustian bargain at 11 years old.

Ira reaches current-day Dave, who is a born-again Christian living with his parents. According to Dave, Bob was at fault for the breakdown in their relationship, because Bob had decided to become friends with someone else.

Host Ira Glass talks with Paul Feig, who as a sixth-grader, at the urging of his father, actually read the Dale Carnegie classic How to Win Friends and Influence People. What he found was that afterwards, he had a bleaker understanding of human nature—and even fewer friends than when he started.

Dishwasher Pete on Letterman.

A case study in every word from a friend meaning its opposite. An excerpt from the short story "The Underminer." A book based on the story is forthcoming from Bloomsbury USA.

Host Ira Glass plays tape of two women who ended up as frenemies.They kept trying to be friends, but couldn't help themselves from fighting. Ira then speaks with psychologist Julianne Holt-Lunstad who has run scientific studies to answer the question: Why don't we simply end these troubling kinds of friendships? Holt-Lunstad's research also shows that these relationships are much more common than you might think.

Katya and Alla are introduced to each other shortly after moving from Russia to a small town outside of Flint, Michigan. The mutual friend who introduces them figures they're both from Russia, they'll obviously hit it off.

Producer Neil Drumming talks with his friend Ta-Nehisi Coates about Ta-Nehisi’s newfound fame and their friendship.

Ira speaks with Professor Glenn Loury. Loury failed to stand up for a light-skinned friend at a black unity rally in the sixties.

A 17 year old tricks an entire resort town into believing he is someone he is not. By Jack Hitt and Christopher Cerf.