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Act One: Lab Rugrats

Continuing from our prologue, host Ira Glass checks in with Lisa and her older daughter, Kennedy, to see how the experiment went. After a month, they've charted surprising results, learned that the girls aren't the only ones in the house who need to change, and found out just how much money it takes to get a twelve-year-old to play with a five-year-old.

Act One: Small Thoughts In Big Brains

This American Life producer Alex Blumberg investigates a little-studied phenomenon: Children who get a mistaken idea in their heads about how something works or what something means, and then don't figure out until well into adulthood that they were wrong. Includes the tale of a girl who received a tissue box for Christmas, allegedly painted by trained monkeys.

Prologue

Kristy Kruger realized in college just how bad her high school education had been. She was always having to pretend she knew what the people around here were talking about when she didn't know.

Prologue

At the Astrodome complex in Houston, charities from Colorado and Florida and other states are competing to take in the hurricane's refugees. But Colorado, which offers the best package of any state, just can't get New Orleans residents to relocate there.

Act Four: Diaspora

Hundreds of thousands of Gulf residents evacuated before the storm and followed the whole thing from afar. Cheryl Wagner left for Gainesville, Florida, where her friends advised her to buy a gun and a mean dog before returning home to New Orleans.

Prologue

Host Ira Glass talks to film critic Jonathan Rosenbaum of the Chicago Reader about an anonymous love letter that turned out to be very different than it seemed.

Act One: The Karachi Kid

When Muhammad Kamran's Pakistani parents sent him off to college in Philadelphia, it was understood that he'd come back to Karachi after four years. But now that graduation is almost here, Muhammad thinks he might want to stay in America.

Prologue

Host Ira Glass talks to Laura Mayer, editor of the New Trier Township High School yearbook, about the renegade student who jumps into as many club photos as he can. And contributing editor Jack Hitt explains how this impulse—to be remembered as someone you're not—can be traced back to Benjamin Franklin.

Prologue

The government had an almost impossible task after the September 11th attacks: They had to try to stop terrorists before they did anything — in some cases, before they even committed a crime. Dr.

Prologue

Host Ira Glass tells the story of Marisela and Yadira, who were honors students in high school. They wanted to go to the best colleges, but they couldn't get federally-funded scholarships because they weren't U.S. citizens; they had come from Mexico when they were little.

Prologue

Host Ira Glass interviews Joe Amrine, who was falsely accused of murder. Rather than avoid the death penalty, Amrine said everything he could think of on the witness stand to get the jury to give him a death sentence.

Act Two: I Am Curious, Jello

About 20 years ago, a Los Angeles prosecutor named Michael Guarino thought he'd make a name for himself by taking the lead singer of the Dead Kennedys to court for obscenity. He was so sure of success, he didn't even bother to listen to the lyrics.

Act Two: Marine Life

Rob Miller is a first lieutenant in the Marine Corps commanding a weapons platoon in "Charlie Company" of the First Battalion, Eighth Marines. He led his men recently in the battle of Fallujah, and in a recent satellite phone call, he told This American Life contributing editor Jack Hitt (who also happens to be his uncle) what we never seem to hear elsewhere: Details of what it's like to fight house-to-house in urban warfare.