Host Ira Glass talks with Susan Dentzer, editor of the journal Health Affairs, about what current health reform proposals do to fix the rising costs of healthcare...And points at a surprising, kind of heartening phenomenon happening within the current debate.

We head to deep inside the natural habitat of frenemies: Reality TV. Rich Juzwiak is a full-time blogger for VH1 and his own pop-culture blog which means he's spent a lot of time watching and dissecting reality TV shows.

Mike Birbiglia explains the chain of events that resulted in him becoming the fall guy for his entire high school, and how it took him a while to catch on to what was happening. This story was recorded live in front of an audience in Cambridge, Mass.

Ira invites Buffy the Vampire Slayer creator Joss Whedon to perform a song from his Dr. Horrible's Sing-Along Blog DVD extra commentary, which is a musical satire that pokes fun at the idea of DVD commentary.

Rany Jazayerli was thrilled when one of his closest friends, Mazen, was hired by the Obama campaign as the liaison to the Muslim community, in the months before the presidential election. It only took 3 weeks for a newspaper to attack his character, and for Mazen to resign from the job of a lifetime.

Back in November, two weeks after he was elected president, Barack Obama delivered a pre-taped speech to an international conference on global warming that was convened in Los Angeles by Governor Arnold Schwarzenegger. It wasn't Obama's most important speech, but the effect it had on the audience was profound—mostly because they heard it through the haze of the last eight years.

Brandon Darby was a radical activist and one of the founders of the incredibly effective relief organization Common Ground. Michael May reports on how Darby changed from a revolutionary who wanted the overthrow of the U.S. government into an informant working with the FBI against his former radical allies.

Planet Money correspondent David Kestenbaum investigates the growing popularity of pet insurance, and what it reveals about insurance for people.

Host Ira Glass talks a veteran police officer about a time in his 20s when he gets sent to a car accident—and it turns out the driver at fault was a nicely dressed chimpanzee. The chimp seemed harmless enough until the other police officer on duty tries to arrest the chimp&'s owner.

For NPR's Adam Davidson, dropping out of college is the worst thing any young person can do in this economy. So when Adam's favorite cousin DJ does just that, Adam brings in a professor of economics from Georgetown University to help persuade DJ to get back on the right track.

Jenifer Hixson tells the story of walking alone at night, and meeting a woman who was out for the very same reason. Jenifer performed the story live in front of an audience at the storytelling series The Moth.

Host Ira Glass describes scenes from a rest stop on the New York State Thruway, the Plattekill Travel Plaza, and the kind of people you might meet if you ever stayed long enough to talk with them. These include Robert Woodhill, the general manager, who needs a good sales day so he can beat his friend Andy, who manages a rest stop in Maine, in their weekly competition.

Host Ira Glass talks with Michael Perrino, a law professor at St Johns University School of Law in New York, who wrote a book about Ferdinand Pecora called The Hellhound of Wall Street. Pecora was the lead attorney in the Senate Banking Committee hearings in the 1930s looking into wrongdoing in the banking industry.

Ira talks with reporter My Thuan Tran of The Los Angeles Times about how San Jose City Councilwoman Madison Nguyen went from being the "golden child" of the Vietnamese community to someone who faced weekly protests and a hunger striker. Turns out red-baiting is alive and well in the Vietnamese-American community.

Host Ira Glass notes the sub-industry in journalism right now of reporting anything that looks like a sign of the recession. He then goes on to list a handful of his own favorites, including a dentist who's seen an increase in broken teeth from grinding, and a decrease in shark attacks.

Dave Hill continues his story. When he talked to a co-worker the morning after his first shift as a night supervisor, he learned that the place isn’t quite what he thought it was.

A couple in Texas find a seemingly abandoned car and think they've stumbled across a crime scene. And they're right...but not in the way they imagined.

Family members can easily be frenemies. You're stuck with them.

The story of a famous but not well-understood political fall guy, someone who became a scapegoat for American policies worldwide. Philip Gourevitch writes about listening to nine hours of interviews with Lynndie England, the American servicewoman photographed at Abu Ghraib prison holding a leash with a naked, Iraqi prisoner on the end of it.

Most of the This American Life production staff spent the weekend at Penn State, and found that drinking is the great unifier at the school. Ira Glass, Sarah Koenig, Lisa Pollak and Jane Feltes report on tailgating parties, frat parties, an article of clothing known as a "fracket," and a surprising and common drunken crime.

Earlier this year, admitted drug user Jorge Cruz decided to act as his own lawyer in an Albany, New York criminal court. Impossibly, he won.

Host Ira Glass talks to Jay Allison, who is in charge of the team at This I Believe, an essay series. Jay wonders why Ira's never contributed an essay about what he believes.