Veronica Chater tells the story of her developmentally disabled brother Vincent, who one day quit his job and then quit everything else, mystifying everyone in his life. Veronica is author of the memoir Waiting for the Apocalypse.

David Sedaris tells a story about his mother who hated home movies, and how his brothers and sisters came to appreciate them. David's the author of several books, including When You Are Engulfed in Flames.

The story of what happens to an average American family, when a perfectly normal, rational and funny mom starts spending every day in the company of an ancient Buddhist monk named Aaron, who no one else can see. Davy Rothbart is one of her three sons, and also the reporter for this story.

Al Jurczynski is the mayor of Schenectady, New York. For the past year, he's embarked on a strange recruitment campaign, to convince Guyanese immigrants living in Queens, New York, to move upstate to Schenectady.

Jonathan Goldstein with a story about friendship, mothers and sons, and what some have called the greatest phone message in the world. Jonathan is the host of the podcast Heavyweight.

Congressman Jesse Jackson, Jr. already had one other man in his life who shared his name—his world famous father, the Jesse Jackson. But then right before his most recent primary race, an aide told him that he now had another Jesse Jackson to contend with.

Host Ira Glass talks with Marion Tanios, a classified section editor at the Chicago Sun-Times. She explains that if the news section of the newspaper gives you the public life of a city, the classified section gives you a sense of people's personal lives.

Jon Ronson tells the story of how his parents decided to commission a family portrait, and how things went awry because of the brilliant but troubled local artist they hired for the job. In the story, Jon circles in a reluctant orbit around his parents, and his parents are in a rather energetic orbit of their own.

Jack Hitt's story about a prison production of Hamlet continues. He discovers that almost all the actors draw on their pasts in one way or another to get into character.

The story from the prologue continues, with the groom who refused to be a groom, and the one person who'll probably remember the fake wedding, namely, the fake bride.

The story of a man who committed a murder when he was a teenager. He got away with it, and didn't tell the police for twenty years.

Host Ira Glass talks with a bunch of special ed students. By and large, they thought of themselves as regular kids—until each experienced a shocking moment of revelation when they discovered that they were not the same as other kids, and that the other kids already knew that...and had known for a long time.

Brent Runyon tells the story of the day in eighth grade that he set himself on fire...and what led to that. He wasn't a loner, he had friends, his mother was a teacher, his parents took an interest in his life.

We hear excerpts from two autobiographies which each describe the same moment, but in very different ways. Elia Kazan and Arthur Miller agree that they met with each other in 1952, around the time Kazan named the names of his old friends to the House Committee on Un-American Activities.

In any family, giving other people what they want becomes fantastically complicated, often because people tend to give others the things they'd like themselves. Curtis Sittenfeld explains how the drama plays out in her family, when it comes to her father's weight.

From the time he was a little kid until the time he graduated high school, Darren Stein made movies with his father's video camera. The cast was composed of friends from his street, a suburban cul-de-sac in Encino, California.

Novelist Miriam Toews, author of The X Letters (which appeared in an earlier episode of the show), tells the story of a road trip she took with her 15-year-old son.

An audio diary of two people using the classified ads to find jobs. Produced by Joe Richman, the awarding winning producer of the series Radio Diaries.

Host Ira Glass talks with NPR's Car Talk hosts Tom and Ray Maggliozi and a former employee of theirs, Joe Richman. Ray once fixed Joe's beloved '72 Plymouth Valiant, a repair job which hastened it to its grave...but probably got Joe a girlfriend.

This American Life senior producer Julie Snyder explains the office politics of street vendors on the corner of Sixth Avenue and Eighth Street in New York City. With her is sociologist Mitch Duneier, who spent years working with the vendors and writing about them for his book Sidewalk.

Jack Hitt begins his story about a group of prisoners at the Missouri Eastern Correctional Center who are rehearsing and staging a production of Hamlet. The man who plays Hamlet gets in character by recalling times he's wanted to hurt people, like the crime that sent him to prison, in which he shot two people and left them for dead.

The story of how common and perfectly legal police interrogation procedures, procedures without violence or torture, were able to get an average fourteen-year-old suburban kid to confess to murdering his own sister...even though DNA evidence later proved that he hadn't done the crime.

In Los Angeles, Cris Beam reports on a family named the Paladinos that had a theory that explained their lives. And then, at some point, that theory came to seem inadequate.

Jonathan Goldstein made every girl he ever dated watch the home movie of his family's Rosh Hashanah dinner he made when he was 17. He hoped that seeing his family life on film might make the women more sympathetic to his shortcomings.