Veronica Chater tells the story of her developmentally disabled brother Vincent, who one day quit his job and then quit everything else, mystifying everyone in his life. Veronica is author of the memoir Waiting for the Apocalypse.

From the time he was a little kid until the time he graduated high school, Darren Stein made movies with his father's video camera. The cast was composed of friends from his street, a suburban cul-de-sac in Encino, California.

The classifieds are populated by people in flux. People selling stuff from old lives in transition new ones.

A fable of how America got its name, and how it was named after someone who was a fraud, but the kind of fraud people love, the kind of fraud who knows how to please a crowd. Jack Hitt tells the racy and little-known story of how Amerigo Vespucci got his name all over the map of the western hemisphere by telling lies about what he found there—the type of lies which can be found today in the pages of Penthouse magazine.

Sure, those who can't do, teach. But what about those who can do? Marlon Brando has created a set of instructional videos about acting, called Lying for a Living. Reporter Jod Kaftan got a sneak preview.

Jon Ronson tells the story of how his parents decided to commission a family portrait, and how things went awry because of the brilliant but troubled local artist they hired for the job. In the story, Jon circles in a reluctant orbit around his parents, and his parents are in a rather energetic orbit of their own.

We hear from a mother and her son. By age seven, he'd had heart failure and been diagnosed as bipolar.

Ira talks with Barry Keenan, who was living a lot of people’s plan A in the early 60’s. He was rich, he was successful.

Host Ira Glass talks with Chris, who worked for a company that helped deaf people talk over the phone with hearing people. The deaf person would type what they wanted Chris to say, and Chris would say it, then type back the response from the hearing person on the line.

Host Ira Glass talks with NPR's Car Talk hosts Tom and Ray Maggliozi and a former employee of theirs, Joe Richman. Ray once fixed Joe's beloved '72 Plymouth Valiant, a repair job which hastened it to its grave...but probably got Joe a girlfriend.

David Cossin's and Allesandra Pomarico's story from the prologue continues. We hear more of David's tapes, and they both tell us how successful the tapes were.

You can't do a program about middlemen without a story about business. In this act, we hear from a man who made his living buying low and selling high...incredibly high, sometimes at mark-ups of up to 1,000 percent.

Reporter Jon Ronson tells the story of how, in the immediate wake of September 11, he became convinced that a man he'd done a story on was responsible for the Anthrax attacks in America. So he did something he'd never done before, he ratted out his source to the FBI.

During the first Gulf War, John Brasfield was an army scout. He went on dangerous missions, in which he was exposed often to enemy fire with little protection.

Brent Runyon tells the story of the day in eighth grade that he set himself on fire...and what led to that. He wasn't a loner, he had friends, his mother was a teacher, his parents took an interest in his life.

Host Ira Glass talks to Cory Simmons and Dominique Mapp, who were driving home one night and were followed by a group of rowdy men in an SUV. The men tailed them for miles and then started firing a gun at them.

How does the Devil work? We hear stories from five different people who say they found themselves inexplicably doing something random and bad, something which made no sense to them at all. Host Ira Glass explains why this might be, cadging a bit from C.S.

The story of how common and perfectly legal police interrogation procedures, procedures without violence or torture, were able to get an average fourteen-year-old suburban kid to confess to murdering his own sister...even though DNA evidence later proved that he hadn't done the crime.

Starlee Kine tells the story of a man more obsessed with reruns than even she is. Director Trent Harris made a movie called The Beaver Trilogy.

Al Jurczynski is the mayor of Schenectady, New York. For the past year, he's embarked on a strange recruitment campaign, to convince Guyanese immigrants living in Queens, New York, to move upstate to Schenectady.